Cognitive Decline Linked To Low Vitamin D - November 2015

Dr Joshua Miller reports their findings that, low vitamin D levels are associated with accelerated decline in episodic memory and executive function, the two cognitive domains strongly associated with Alzheimer's disease (AD) dementia, a new study indicates. "The magnitude of the effect of Vitamin D insufficiency on cognition was substantial," the research team concluded. "There is recent and growing literature on the associations between vitamin D status and risk of Alzheimer's disease/dementia, cognitive decline, and brain atrophy. "Intelligently designed trials," added Dr Llewellyn, "are now needed which target people who are both likely to be vitamin D–deficient and cognitively decline within a reasonable follow-up period. Vitamin D supplementation remains an intriguing possibility to delay or even prevent dementia."

JAMA Neurol. Published online September 14, 2015. Abstract

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